STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIG4DNA ligase. (2563 aa)    
Predicted Functional Partners:
Xrcc5
X-ray repair cross-complementing protein 5.
   
 0.990
PCNA
Proliferating cell nuclear antigen.
  
 0.988
XRCC1
DNA repair protein XRCC1.
   
 0.952
ERCC5
DNA repair protein.
  
 0.946
POLL
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  
 0.928
Pnkp
Bifunctional polynucleotide phosphatase/kinase.
   
 0.906
T03_6160
Uncharacterized protein.
    
 0.899
CNPPD1
Protein CNPPD1.
    
 0.899
T03_17700
Uncharacterized protein.
    
 0.899
MRE11A
Tyrosine 3-monooxygenase.
  
 0.899
Your Current Organism:
Trichinella britovi
NCBI taxonomy Id: 45882
Other names: T. britovi
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