| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CLOAM1492 | obg | CLOAM1492 | CLOAM0122 | Putative enzyme with radical SAM domain protein (Fe-S oxidoreductases); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.893 |
| obg | CLOAM1492 | CLOAM0122 | CLOAM1492 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Putative enzyme with radical SAM domain protein (Fe-S oxidoreductases); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.893 |
| obg | rluA | CLOAM0122 | CLOAM1454 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.845 |
| obg | rplI | CLOAM0122 | CLOAM1606 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.818 |
| obg | rplK | CLOAM0122 | CLOAM0460 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.888 |
| obg | rplQ | CLOAM0122 | CLOAM1112 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L17. | 0.841 |
| obg | rplT | CLOAM0122 | CLOAM0531 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.908 |
| obg | rplU | CLOAM0122 | CLOAM0293 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.879 |
| obg | rpmA | CLOAM0122 | CLOAM0292 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal subunit protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.901 |
| obg | rpmF | CLOAM0122 | CLOAM0257 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.836 |
| obg | rsfS | CLOAM0122 | CLOAM0360 | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.907 |
| rluA | obg | CLOAM1454 | CLOAM0122 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.845 |
| rluA | rplI | CLOAM1454 | CLOAM1606 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.578 |
| rluA | rplK | CLOAM1454 | CLOAM0460 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.889 |
| rluA | rplQ | CLOAM1454 | CLOAM1112 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L17. | 0.898 |
| rluA | rplU | CLOAM1454 | CLOAM0293 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.901 |
| rluA | rpmF | CLOAM1454 | CLOAM0257 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.474 |
| rluA | rsfS | CLOAM1454 | CLOAM0360 | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.912 |
| rplI | obg | CLOAM1606 | CLOAM0122 | Ribosomal protein L9; Binds to the 23S rRNA. | DNA-binding GTPase involved in cell partioning; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.818 |
| rplI | rluA | CLOAM1606 | CLOAM1454 | Ribosomal protein L9; Binds to the 23S rRNA. | Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.578 |