STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase (leucine aminopeptidase) (LAP) (leucyl aminopeptidase) (aminopeptidase A/I); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (493 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.833
aspC
Aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  0.830
CLOAM1245
Aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
  0.830
CLOAM0983
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
   
  0.825
CLOAM1025
class-II pyridoxal-phosphate-dependent aminotransferase (malY/patB-like); Function of strongly homologous gene; enzyme.
  
 
  0.810
CLOAM0132
Hypothetical protein; No homology to any previously reported sequences.
  
    0.687
CLOAM0133
Hypothetical protein; No homology to any previously reported sequences.
       0.678
CLOAM0134
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.678
CLOAM0137
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.439
pepP
Xaa-Pro aminopeptidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.436
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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