Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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dapFDiaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (262 aa)    
Predicted Functional Partners:
lysA
Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.945
dapB
Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
   
 0.942
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
    
 0.939
CLOAM0632
Putative Metal-dependent amidase/aminoacylase/carboxypeptidase.
    
 0.921
dapA
Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.794
CLOAM0283
Hypothetical protein; No homology to any previously reported sequences.
       0.793
CLOAM0280
Putative peptidase T (tripeptide aminopeptidase) (aminotripeptidase) (tripeptidase) (yqjE); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.782
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
      0.592
lysC
Aspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
 
  
 0.587
asd
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.530
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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