Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lysCAspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (405 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.984
metG
Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.872
aspC
Aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.856
CLOAM1245
Aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 
 0.856
CLOAM0669
Putative Asparagine synthase (glutamine-hydrolyzing); No homology to any previously reported sequences.
  
 
 0.853
asnB
Asparagine synthetase (Glutamine-hydrolyzing); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.853
purA
Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.835
ansB
L-asparaginase (L-asparagine amidohydrolase) (L-ASNase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.822
CLOAM0357
Putative NADH-dependent fumarate reductase (frd); Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.815
pyrB
Aspartate carbamoyltransferase (aspartate transcarbamylase) (ATCase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
 0.802
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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