Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pfk6-phosphofructokinase (ATP-dependent phosphofructokinase) (ATP-PFK); Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (365 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; Belongs to the GPI family.
  
 0.960
fbaA
Fructose-bisphosphate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.949
CLOAM1259
Putative Transketolase.
  
 0.924
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
0.913
CLOAM1580
Putative mannose-6-phosphate isomerase.
    
 0.911
gapA
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.664
ccmA1
ABC-type multidrug transport system, ATPase component.
 
    0.627
nosY
ABC-type transport system involved in multi-copper enzyme maturation, permease component.
  
    0.621
CLOAM0620
Hypothetical protein; No homology to any previously reported sequences; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.613
CLOAM0623
Hypothetical protein; No homology to any previously reported sequences.
       0.613
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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