Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CLOAM0708Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (127 aa)    
Predicted Functional Partners:
aorA
Tungsten-containing aldehyde ferredoxin oxidoreductase, alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.992
tufB
Protein chain elongation factor EF-Tu (duplicate of tufA); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.872
hymC
[Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.731
CLOAM1488
Putative Molybdopterin-guanine dinucleotide biosynthesis protein B.
 
     0.715
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.702
CLOAM0324
Pyruvate-ferredoxin/flavodoxin oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.590
CLOAM0707
Hypothetical protein; No homology to any previously reported sequences.
       0.590
CLOAM1684
Formate dehydrogenase major subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.489
CLOAM1250
Putative 4Fe-4S ferredoxin-type protein (yccM); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
  
  
 0.483
CLOAM1631
Dihydropyrimidine dehydrogenase (NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.447
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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