| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CLOAM0765 | CLOAM1877 | CLOAM0765 | CLOAM1877 | Hypothetical protein; No homology to any previously reported sequences. | Putative formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | 0.525 |
| CLOAM0765 | metG | CLOAM0765 | CLOAM0440 | Hypothetical protein; No homology to any previously reported sequences. | Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.506 |
| CLOAM0765 | ruvA | CLOAM0765 | CLOAM0929 | Hypothetical protein; No homology to any previously reported sequences. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.435 |
| CLOAM0765 | uvrA | CLOAM0765 | CLOAM0971 | Hypothetical protein; No homology to any previously reported sequences. | ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.556 |
| CLOAM0765 | uvrB | CLOAM0765 | CLOAM0820 | Hypothetical protein; No homology to any previously reported sequences. | Excinulease of nucleotide excision repair, DNA damage recognition component; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. I [...] | 0.902 |
| CLOAM0765 | uvrC | CLOAM0765 | CLOAM0791 | Hypothetical protein; No homology to any previously reported sequences. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.918 |
| CLOAM0765 | uvrD | CLOAM0765 | CLOAM0549 | Hypothetical protein; No homology to any previously reported sequences. | Superfamily I DNA and RNA helicases. | 0.452 |
| CLOAM0793 | CLOAM0794 | CLOAM0793 | CLOAM0794 | Putative DNA polymerase III, delta prime subunit (holB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acetyltransferase, GNAT family. | 0.785 |
| CLOAM0793 | metG | CLOAM0793 | CLOAM0440 | Putative DNA polymerase III, delta prime subunit (holB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.414 |
| CLOAM0793 | murJ | CLOAM0793 | CLOAM0792 | Putative DNA polymerase III, delta prime subunit (holB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.773 |
| CLOAM0793 | uvrC | CLOAM0793 | CLOAM0791 | Putative DNA polymerase III, delta prime subunit (holB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.789 |
| CLOAM0794 | CLOAM0793 | CLOAM0794 | CLOAM0793 | Acetyltransferase, GNAT family. | Putative DNA polymerase III, delta prime subunit (holB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.785 |
| CLOAM0794 | murJ | CLOAM0794 | CLOAM0792 | Acetyltransferase, GNAT family. | Conserved hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.776 |
| CLOAM0794 | uvrC | CLOAM0794 | CLOAM0791 | Acetyltransferase, GNAT family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.773 |
| CLOAM1877 | CLOAM0765 | CLOAM1877 | CLOAM0765 | Putative formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | Hypothetical protein; No homology to any previously reported sequences. | 0.525 |
| CLOAM1877 | ruvA | CLOAM1877 | CLOAM0929 | Putative formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.438 |
| CLOAM1877 | uvrC | CLOAM1877 | CLOAM0791 | Putative formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.525 |
| metG | CLOAM0765 | CLOAM0440 | CLOAM0765 | Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Hypothetical protein; No homology to any previously reported sequences. | 0.506 |
| metG | CLOAM0793 | CLOAM0440 | CLOAM0793 | Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Putative DNA polymerase III, delta prime subunit (holB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.414 |
| metG | uvrC | CLOAM0440 | CLOAM0791 | Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.506 |
