Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pgk3-phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (423 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.997
gapA
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.995
CLOAM1530
Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.993
eno
Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.981
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.972
fbaA
Fructose-bisphosphate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.925
pgi
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; Belongs to the GPI family.
  
 
 0.888
ppdK
Pyruvate phosphate dikinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PEP-utilizing enzyme family.
    
 0.830
CLOAM1531
Putative Pyruvate phosphate dikinase,PEP/pyruvate-binding:PEP-utilising enzyme, mobile region.
    
 0.830
CLOAM1259
Putative Transketolase.
  
 
 0.726
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
Server load: low (34%) [HD]