STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLOAM0806Putative bifunctional signal transducer for sigma factor regulation / phosphoserine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (638 aa)    
Predicted Functional Partners:
CLOAM1190
Anti-sigma regulatory factor (Ser/Thr protein kinase) (modular protein).
  
 
 0.935
hydG
Fe-hydrogenase assembly protein,S-adenosylmethionine radical protein; Function of strongly homologous gene; enzyme.
   
  
 0.896
CLOAM0807
Putative ABC transporter substrate-binding protein.
 
   
 0.893
CLOAM0888
Hypothetical protein; No homology to any previously reported sequences.
 
 
 0.816
CLOAM1618
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.762
CLOAM1875
Hypothetical protein; No homology to any previously reported sequences.
  
  
 0.702
CLOAM1048
Putative Protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.569
CLOAM0390
Hypothetical protein; No homology to any previously reported sequences.
  
    0.507
glyA
Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.499
serC
Phosphoserine aminotransferase (PSAT) (phosphoserine transaminase); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
     
  0.499
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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