STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (344 aa)    
Predicted Functional Partners:
cas2
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.992
CLOAM0853
Hypothetical protein; No homology to any previously reported sequences.
 
     0.887
cas2-2
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.865
CLOAM1200
RNA-directed DNA polymerase (Reverse transcriptase).
      0.856
CLOAM1291
Putative CRISPR-associated helicase Cas3, core.
 
  
 0.820
CLOAM1293
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.795
CLOAM0854
Hypothetical protein; No homology to any previously reported sequences.
       0.776
CLOAM1288
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 
 0.741
CLOAM0857
Hypothetical protein; No homology to any previously reported sequences.
       0.737
CLOAM0858
Hypothetical protein; No homology to any previously reported sequences.
       0.737
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.