Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
miaBtRNA-i(6)A37 modification enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (427 aa)    
Predicted Functional Partners:
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
 0.876
CLOAM0904
Hypothetical protein; No homology to any previously reported sequences.
  
    0.779
CLOAM0902
Putative enzyme with radical SAM domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.765
CLOAM0900
Hypothetical protein; Doubtful CDS.
       0.762
CLOAM0901
Putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
       0.762
CLOAM0903
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.762
CLOAM1242
Putative radical SAM-dependent enzyme (yfgB); Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
 
  
 0.683
CLOAM0928
Putative 16S rRNA m5C967 methyltransferase,S-adenosyl-L-methionine-dependent; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.591
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase); Function of strongly homologous gene; enzyme.
    
 0.581
CLOAM0896
TRNA-uridine 2-sulfurtransferase; Putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase / fibronectin/fibrinogen-binding protein.
  
  
 0.521
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.