STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLOAM0919Putative Histidinol-phosphatase; Homologs of previously reported genes of unknown function; Belongs to the PHP hydrolase family. HisK subfamily. (246 aa)    
Predicted Functional Partners:
CLOAM0138
Putative aromatic amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.925
CLOAM0915
Putative ApbE-like lipoprotein precursor; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
       0.776
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
       0.773
CLOAM0917
Putative zinc protease (metalloendopeptidase) (ymxG module); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M16 family.
       0.773
hgdC
Activator of (R)-2-hydroxyglutaryl-CoA dehydratase; Function of homologous gene experimentally demonstrated in an other organism; regulator.
       0.773
CLOAM0914
Hypothetical protein; No homology to any previously reported sequences.
       0.741
CLOAM0913
Putative B12-dependent ribonucleoside-diphosphate/-triphosphate reductase (nrdJ-like); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
  
 0.559
kce
3-keto-5-aminohexanoate cleavage enzyme; Involved in the anaerobic fermentation of lysine. Catalyzes the reversible reaction between 3-keto-5-aminohexanoate (KAH) and acetyl-CoA to form 3-aminobutyryl-CoA and acetoacetate. The reaction involves the deprotonation of KAH, the nucleophilic addition onto acetyl-CoA and the intramolecular transfer of the CoA moiety. Belongs to the KCE family.
       0.525
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
    0.459
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.421
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.