Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ansBL-asparaginase (L-asparagine amidohydrolase) (L-ASNase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (325 aa)    
Predicted Functional Partners:
aspC
Aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.915
CLOAM1245
Aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
    
 0.915
CLOAM0669
Putative Asparagine synthase (glutamine-hydrolyzing); No homology to any previously reported sequences.
     
 0.910
asnB
Asparagine synthetase (Glutamine-hydrolyzing); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.910
CLOAM0357
Putative NADH-dependent fumarate reductase (frd); Catalyzes the oxidation of L-aspartate to iminoaspartate.
   
 
 0.907
purA
Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.904
pyrB
Aspartate carbamoyltransferase (aspartate transcarbamylase) (ATCase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
    
  0.900
panD
Aspartate 1-decarboxylase precursor (Aspartate alpha-decarboxylase); Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.855
lysC
Aspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
     
 0.822
ftcd
Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.800
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.