Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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glmSGlutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa)    
Predicted Functional Partners:
CLOAM1490
Glutamine---fructose-6-phosphate transaminase (isomerizing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 
0.928
CLOAM1784
Similar to Biotin carboxylase.
   
 0.927
glnA
Glutamine synthetase (glutamate--ammonia ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glutamine synthetase family.
  
 
 0.923
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
0.916
pgi
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; Belongs to the GPI family.
  
 
 0.916
CLOAM1580
Putative mannose-6-phosphate isomerase.
     
 0.911
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
    
 0.909
CLOAM0363
Bifunctional glmU protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.782
ccmA
ABC-type multidrug transport system, ATPase component.
     
 0.775
CLOAM0956
Hypothetical protein; No homology to any previously reported sequences.
       0.773
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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