STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLOAM0963Putative dye-linked L-proline dehydrogenase (pdhB); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (384 aa)    
Predicted Functional Partners:
CLOAM0964
Putative dye-linked L-proline dehydrogenase (pdhA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.994
glyA
Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.930
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
 
 0.916
gcvPB
Probable glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
 
 0.916
gcvPA
Probable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
   
 
 0.909
CLOAM1665
Low-specificity L-threonine aldolase.
    
 0.909
gcvT
Aminomethyltransferase (Glycine cleavage system T protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GcvT family.
  
 
 0.855
aorA
Tungsten-containing aldehyde ferredoxin oxidoreductase, alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.614
CLOAM0882
Alanine racemase (partial match, alr-like); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
 0.564
CLOAM0437
Hypothetical protein; No homology to any previously reported sequences.
  
   
 0.483
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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