Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mafMaf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (171 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase (NDK) (NDP kinase) (nucleoside-2-P kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
  0.912
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.908
pyrG
CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
   
  0.908
pyrR
Bifunctional protein : Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
    
  0.904
CLOAM0819
Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase).
    
  0.901
nrdD
Ribonucleoside-triphosphate reductase (formate); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.901
udk
Uridine kinase.
    
  0.901
pyrH
Uridylate kinase (UK) (uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
  0.901
tdk
Thymidine kinase.
     
  0.900
CLOAM0524
Putative 5'-nucleotidase; No homology to any previously reported sequences; Belongs to the 5'-nucleotidase family.
     
  0.900
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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