| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CLOAM1006 | pyrE | CLOAM1006 | CLOAM1005 | Hypothetical protein; No homology to any previously reported sequences. | Fused protein: Orotate phosphoribosyltransferase (pyrE-like) (C_terminal); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.503 |
| CLOAM1006 | rnhB | CLOAM1006 | CLOAM1007 | Hypothetical protein; No homology to any previously reported sequences. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.784 |
| CLOAM1069 | rnhB | CLOAM1069 | CLOAM1007 | Putative lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.920 |
| CLOAM1203 | CLOAM1536 | CLOAM1203 | CLOAM1536 | Putative HRDC domain protein. | Putative DNA polymerase III, beta chain (dnaN-like); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is require [...] | 0.633 |
| CLOAM1203 | dinG | CLOAM1203 | CLOAM1545 | Putative HRDC domain protein. | Putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase); 3'-5' exonuclease. | 0.685 |
| CLOAM1203 | polA | CLOAM1203 | CLOAM1364 | Putative HRDC domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.945 |
| CLOAM1203 | rnhB | CLOAM1203 | CLOAM1007 | Putative HRDC domain protein. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.639 |
| CLOAM1536 | CLOAM1203 | CLOAM1536 | CLOAM1203 | Putative DNA polymerase III, beta chain (dnaN-like); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is require [...] | Putative HRDC domain protein. | 0.633 |
| CLOAM1536 | dinG | CLOAM1536 | CLOAM1545 | Putative DNA polymerase III, beta chain (dnaN-like); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is require [...] | Putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase); 3'-5' exonuclease. | 0.682 |
| CLOAM1536 | polA | CLOAM1536 | CLOAM1364 | Putative DNA polymerase III, beta chain (dnaN-like); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is require [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
| CLOAM1536 | rnhB | CLOAM1536 | CLOAM1007 | Putative DNA polymerase III, beta chain (dnaN-like); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is require [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.873 |
| dinG | CLOAM1203 | CLOAM1545 | CLOAM1203 | Putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase); 3'-5' exonuclease. | Putative HRDC domain protein. | 0.685 |
| dinG | CLOAM1536 | CLOAM1545 | CLOAM1536 | Putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase); 3'-5' exonuclease. | Putative DNA polymerase III, beta chain (dnaN-like); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is require [...] | 0.682 |
| dinG | polA | CLOAM1545 | CLOAM1364 | Putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase); 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.951 |
| dinG | rnhB | CLOAM1545 | CLOAM1007 | Putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase); 3'-5' exonuclease. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.776 |
| dnaJ | hymB | CLOAM0758 | CLOAM1183 | Chaperone protein DnaJ (Heat shock protein 40) (HSP40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.979 |
| dnaJ | polA | CLOAM0758 | CLOAM1364 | Chaperone protein DnaJ (Heat shock protein 40) (HSP40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.624 |
| dnaJ | rnhB | CLOAM0758 | CLOAM1007 | Chaperone protein DnaJ (Heat shock protein 40) (HSP40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.644 |
| hymB | dnaJ | CLOAM1183 | CLOAM0758 | [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Chaperone protein DnaJ (Heat shock protein 40) (HSP40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.979 |
| hymB | rnhB | CLOAM1183 | CLOAM1007 | [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.913 |