Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CLOAM1017Putative Protein-tyrosine-phosphatase; No homology to any previously reported sequences; Belongs to the SUA5 family. (394 aa)    
Predicted Functional Partners:
trx
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.794
CLOAM1018
Putative metalloendopeptidase (envC); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.780
purL
Phosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
  
  
 0.774
CLOAM1638
Predicted ATPase or kinase.
 
  
 0.734
tsaD
Putative metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.729
CLOAM0434
Putative Non-specific protein-tyrosine kinase; No homology to any previously reported sequences.
  
 
 0.702
CLOAM1019
Putative ABC transporter, transmembrane region:ABC transporter related.
   
 
 0.684
CLOAM1020
Putative ABC transporter (membrane (N-terminal),atp_bind (C-terminal)); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 
 0.684
CLOAM1370
Putative Peptidase M22, glycoprotease.
    
 0.680
CLOAM0610
Hypothetical protein; No homology to any previously reported sequences.
    
 
 0.661
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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