STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhBNAD-specific glutamate dehydrogenase (NAD-GDH) (NADH-dependent glutamate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)    
Predicted Functional Partners:
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase); Function of strongly homologous gene; enzyme.
  
 0.937
CLOAM1799
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.931
npdA
NAD-dependent deacetylase (Regulatory protein SIR2 homolog); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily.
   
 0.929
glnA
Glutamine synthetase (glutamate--ammonia ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glutamine synthetase family.
  
 
 0.928
aspC
Aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.917
CLOAM1245
Aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 
 0.917
hcp
Hydroxylamine reductase (Hybrid-cluster protein) (HCP); Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.915
cpkA
Carbamate kinase (carbamate kinase-like) (carbamate kinase-like carbamoylphosphate synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family.
     
 0.912
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
    
  0.906
lpdA
Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.888
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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