Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
CLOAM1500Hypothetical protein; No homology to any previously reported sequences. (605 aa)    
Predicted Functional Partners:
CLOAM1502
Putative zinc metallopeptidase.
 
     0.807
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
       0.773
kamE
L-beta-lysine 5,6-aminomutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.675
kamD
L-beta-lysine 5,6-aminomutase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.675
CLOAM0383
Putative tungsten-containing aldehyde ferredoxin oxidoreductase cofactor modifying protein (cmo); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.663
CLOAM0388
Hypothetical protein; No homology to any previously reported sequences.
  
     0.552
CLOAM1386
Hypothetical protein; No homology to any previously reported sequences.
 
 
 0.518
CLOAM0108
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.507
CLOAM1658
Hypothetical protein; No homology to any previously reported sequences.
  
     0.503
CLOAM1659
Hypothetical protein; No homology to any previously reported sequences.
  
     0.493
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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