STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kamDL-beta-lysine 5,6-aminomutase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (518 aa)    
Predicted Functional Partners:
kamE
L-beta-lysine 5,6-aminomutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
kdd
3,5-diaminohexanoate dehydrogenase; Function experimentally demonstrated in the studied organism; enzyme.
 
 
 0.979
kamA
L-lysine 2,3-aminomutase (KAM) (LAM); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.918
CLOAM1350
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.798
kce
3-keto-5-aminohexanoate cleavage enzyme; Involved in the anaerobic fermentation of lysine. Catalyzes the reversible reaction between 3-keto-5-aminohexanoate (KAH) and acetyl-CoA to form 3-aminobutyryl-CoA and acetoacetate. The reaction involves the deprotonation of KAH, the nucleophilic addition onto acetyl-CoA and the intramolecular transfer of the CoA moiety. Belongs to the KCE family.
 
   
 0.756
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
  
    0.695
CLOAM1500
Hypothetical protein; No homology to any previously reported sequences.
       0.675
CLOAM1502
Putative zinc metallopeptidase.
       0.675
deoA
Thymidine phosphorylase.
  
 
 0.666
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase); Function of strongly homologous gene; enzyme.
  
 
 0.411
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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