STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscSCysteine desulfurase (ThiI transpersulfidase) (NifS protein homolog); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (396 aa)    
Predicted Functional Partners:
CLOAM1692
Putative iron-sulfur cluster assembly scaffold (IscU module); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
 0.999
CLOAM1487
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative enzyme.
   
 0.871
CLOAM1030
NifU-like domain protein.
  
 
 0.707
acpP
Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.661
CLOAM0680
Putative acyl carrier protein (acpP-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
    
 
 0.661
dnaK
Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.655
clpP
Proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
 
 0.583
hslU
Molecular chaperone and ATPase component of HslUV protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.
 
 
  
 0.499
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
  
 0.486
CLOAM1693
Hypothetical protein; No homology to any previously reported sequences.
       0.485
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.