STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mreBCell wall structural complex MreBCD, actin-like component MreB. (345 aa)    
Predicted Functional Partners:
CLOAM1806
Hypothetical protein; No homology to any previously reported sequences.
 
 
 0.981
mrdA
Penicillin-binding protein 2 (PBP-2); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.944
CLOAM0283
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.933
rodA
Rod shape-determining protein RodA; Belongs to the SEDS family.
 
 
 0.913
ftsZ
Cell division protein FtsZ, tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.694
CLOAM1084
Hypothetical protein; No homology to any previously reported sequences.
  
   0.623
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.594
CLOAM0324
Pyruvate-ferredoxin/flavodoxin oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.593
CLOAM1805
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.587
CLOAM1804
Hypothetical protein; No homology to any previously reported sequences.
       0.580
Your Current Organism:
Cloacimonas acidaminovorans
NCBI taxonomy Id: 459349
Other names: C. Cloacimonas acidaminovorans str. Evry, Candidatus Cloacamonas acidaminovorans str. Evry, Candidatus Cloacimonas acidaminovorans str. Evry
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.