STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN46428.1Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. (126 aa)    
Predicted Functional Partners:
SDN63729.1
ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.
  
 
 0.712
SDM44331.1
ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family.
  
 
 0.712
SDN39737.1
ATP-dependent Clp protease ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family.
  
 
 0.712
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.509
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.501
SDN47078.1
Plasmid segregation protein ParM.
  
 
 0.490
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.483
hslV
ATP dependent peptidase CodWX, CodW component. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.458
SDM89454.1
UPF0716 protein FxsA.
   
    0.412
SDM63748.1
Serine/threonine protein kinase.
   
 
 0.411
Your Current Organism:
Fictibacillus solisalsi
NCBI taxonomy Id: 459525
Other names: Bacillus solisalsi, Bacillus solisalsi Liu et al. 2009, Bacillus sp. V11SED5, CGMCC 1.6854, F. solisalsi, Fictibacillus solisalsi (Liu et al. 2009) Glaeser et al. 2013, JCM 14863, KCTC 13181, strain YC1
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