STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UF70_0718Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (234 aa)    
Predicted Functional Partners:
UF70_0720
Phosphoribosyl-AMP cyclohydrolase.
  
 0.999
UF70_0716
Imidazoleglycerol-phosphate dehydratase.
 
  
 0.998
UF70_0717
Imidazole glycerol phosphate synthase amidotransferase subunit.
 
  
 0.996
UF70_0714
ATP phosphoribosyltransferase.
 
  
 0.995
UF70_0715
Histidinol dehydrogenase.
 
  
 0.995
UF70_0719
Imidazole glycerol phosphate synthase cyclase subunit.
  
0.995
UF70_0713
ATP phosphoribosyltransferase regulatory subunit.
  
  
 0.959
hisC
Biosynthetic Aromatic amino acid aminotransferase beta; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
  
 0.916
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.689
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.680
Your Current Organism:
Staphylococcus pasteuri
NCBI taxonomy Id: 45972
Other names: ATCC 51129, CCUG 32420, CIP 103540, DSM 10656, S. pasteuri, strain BM9357
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