Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cyaB_1Guanylate cyclase. (364 aa)    
Predicted Functional Partners:
luxQ_1
Sensory histidine-kinase / response regulator.
 0.998
bvgS
Sensory box histidine kinase/response regulator.
 0.998
arcB_1
Sensory box histidine kinase/response regulator.
 0.998
letS
Legionella transmission sensor LetS.
 
 0.990
gmr_1
Regulatory protein (GGDEF domain).
 
 0.981
gmr_2
Inner membrane protein/sensory box protein LssE.
 0.976
evgS
Sensory box histidine kinase/response regulator.
 
 0.970
cph2_2
Regulatory protein (GGDEF, PAS, PAC domains).
  
 0.955
arcB_2
Sensory box sensor histidine kinase/response regulator.
 0.951
zraS
Signal transduction histidine kinase.
 
 
 0.946
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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