| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lstg_2834 | glyA | Lstg_2834 | Lstg_1040 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.910 |
| Lstg_2834 | trpA | Lstg_2834 | Lstg_0194 | Phosphoserine phosphatase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.872 |
| Lstg_2834 | trpB | Lstg_2834 | Lstg_0193 | Phosphoserine phosphatase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.892 |
| Lstg_2834 | trpC | Lstg_2834 | Lstg_0411 | Phosphoserine phosphatase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.490 |
| Lstg_2834 | trpF | Lstg_2834 | Lstg_0192 | Phosphoserine phosphatase. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.437 |
| glyA | Lstg_2834 | Lstg_1040 | Lstg_2834 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.910 |
| glyA | trpA | Lstg_1040 | Lstg_0194 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.885 |
| glyA | trpB | Lstg_1040 | Lstg_0193 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.885 |
| glyA | trpE | Lstg_1040 | Lstg_0282 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase. | 0.400 |
| glyA | trpF | Lstg_1040 | Lstg_0192 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.444 |
| lgt | trpA | Lstg_2174 | Lstg_0194 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.912 |
| lgt | trpB | Lstg_2174 | Lstg_0193 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.893 |
| pabB | trpA | Lstg_0667 | Lstg_0194 | Para-aminobenzoate synthase, component I. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.966 |
| pabB | trpB | Lstg_0667 | Lstg_0193 | Para-aminobenzoate synthase, component I. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.976 |
| pabB | trpC | Lstg_0667 | Lstg_0411 | Para-aminobenzoate synthase, component I. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.997 |
| pabB | trpD | Lstg_0667 | Lstg_0410 | Para-aminobenzoate synthase, component I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.998 |
| pabB | trpE | Lstg_0667 | Lstg_0282 | Para-aminobenzoate synthase, component I. | Anthranilate synthase. | 0.991 |
| pabB | trpF | Lstg_0667 | Lstg_0192 | Para-aminobenzoate synthase, component I. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.966 |
| pabB | trpG | Lstg_0667 | Lstg_0409 | Para-aminobenzoate synthase, component I. | Anthranilate synthase component II. | 0.999 |
| trpA | Lstg_2834 | Lstg_0194 | Lstg_2834 | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Phosphoserine phosphatase. | 0.872 |
