Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
apxIBToxin secretion ABC transporter ATP-binding protein. (522 aa)    
Predicted Functional Partners:
cvaA
Putative membrane fusion protein.
 0.984
Lstg_0486
Outer membrane component of multidrug efflux pump.
 
 
  0.969
tolC
Outer membrane protein TolC.
  
 
 0.845
gltR
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.816
Lstg_0491
Hypothetical protein; Belongs to the UPF0753 family.
 
     0.797
Lstg_0493
Hypothetical protein.
 
     0.797
Lstg_3386
Hypothetical protein.
  
 
 0.788
nuoL_1
NADH-ubiquinone oxidoreductase chain 5.
  
    0.721
Lstg_0550
Agglutination protein.
  
 
 0.692
Lstg_1834
Outer membrane efflux protein.
  
 
 0.692
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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