| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hemL | mnmC | Lstg_0641 | Lstg_0639 | Glutamate-1-semialdehyde-2,1-aminomutase. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.704 |
| hemL | prpB | Lstg_0641 | Lstg_0638 | Glutamate-1-semialdehyde-2,1-aminomutase. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.543 |
| hemL | prpC | Lstg_0641 | Lstg_0637 | Glutamate-1-semialdehyde-2,1-aminomutase. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.435 |
| hemL | rubR | Lstg_0641 | Lstg_0642 | Glutamate-1-semialdehyde-2,1-aminomutase. | Rubredoxin. | 0.798 |
| hemL | ydgR | Lstg_0641 | Lstg_0640 | Glutamate-1-semialdehyde-2,1-aminomutase. | Peptide transport protein. | 0.704 |
| lysP_1 | ydgR | Lstg_1329 | Lstg_0640 | Amino acid (lysine) permease. | Peptide transport protein. | 0.458 |
| lysP_1 | yveA_1 | Lstg_1329 | Lstg_2297 | Amino acid (lysine) permease. | Amino acid permease. | 0.533 |
| macB_2 | ydgR | Lstg_2485 | Lstg_0640 | ABC transporter permease. | Peptide transport protein. | 0.458 |
| mnmC | hemL | Lstg_0639 | Lstg_0641 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.704 |
| mnmC | prpB | Lstg_0639 | Lstg_0638 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.789 |
| mnmC | prpC | Lstg_0639 | Lstg_0637 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.766 |
| mnmC | prpD | Lstg_0639 | Lstg_0636 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 2-methylcitrate dehydratase. | 0.667 |
| mnmC | rubR | Lstg_0639 | Lstg_0642 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Rubredoxin. | 0.444 |
| mnmC | ydgR | Lstg_0639 | Lstg_0640 | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | Peptide transport protein. | 0.830 |
| ppnK | ydgR | Lstg_1476 | Lstg_0640 | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Peptide transport protein. | 0.560 |
| prpB | hemL | Lstg_0638 | Lstg_0641 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.543 |
| prpB | mnmC | Lstg_0638 | Lstg_0639 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.789 |
| prpB | prpC | Lstg_0638 | Lstg_0637 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.995 |
| prpB | prpD | Lstg_0638 | Lstg_0636 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 2-methylcitrate dehydratase. | 0.994 |
| prpB | ydgR | Lstg_0638 | Lstg_0640 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | Peptide transport protein. | 0.721 |
