Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
mdtAMultidrug efflux system, subunit A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (411 aa)    
Predicted Functional Partners:
mdtB
Multidrug efflux system, subunit B; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.981
mdtC_2
Multidrug efflux system, subunit C; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.980
ttgC_2
Outer membrane efflux protein.
 
  0.958
cusA_1
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.855
lmxF
Multidrug efflux pump.
  
  0.853
tolC
Outer membrane protein TolC.
   
 0.848
oprM_2
Outer membrane efflux protein.
  
  0.846
oprM_4
Outer membrane efflux protein.
  
  0.823
oprM_3
Outer membrane efflux protein.
  
  0.815
czcA_1
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  0.798
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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