tdcF protein (Legionella steigerwaltii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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gene co-occurrence

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Your Current Organism:

Legionella steigerwaltii

NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lstg_0948	rpoZ	Lstg_0948	Lstg_0952	Hypothetical protein.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.627
Lstg_0948	spoT	Lstg_0948	Lstg_0951	Hypothetical protein.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.716
Lstg_0948	tdcF	Lstg_0948	Lstg_0950	Hypothetical protein.	L-PSP (mRNA) endoribonuclease.	0.716
Lstg_0948	uup_1	Lstg_0948	Lstg_0949	Hypothetical protein.	ABC transporter ATP-binding protein.	0.829
budB	tdcF	Lstg_2727	Lstg_0950	Acetolactate synthase; Belongs to the TPP enzyme family.	L-PSP (mRNA) endoribonuclease.	0.721
fusA_1	rpoZ	Lstg_0317	Lstg_0952	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.784
fusA_1	tdcF	Lstg_0317	Lstg_0950	Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]	L-PSP (mRNA) endoribonuclease.	0.575
gmk	rph	Lstg_0953	Lstg_0956	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.568
gmk	rpoZ	Lstg_0953	Lstg_0952	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.955
gmk	spoT	Lstg_0953	Lstg_0951	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.963
gmk	tdcF	Lstg_0953	Lstg_0950	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	L-PSP (mRNA) endoribonuclease.	0.722
gmk	trpE	Lstg_0953	Lstg_0282	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Anthranilate synthase.	0.575
gmk	uup_1	Lstg_0953	Lstg_0949	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	ABC transporter ATP-binding protein.	0.469
gmk	yicC	Lstg_0953	Lstg_0954	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Putative stress-induced protein.	0.934
rph	gmk	Lstg_0956	Lstg_0953	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.568
rph	rpoZ	Lstg_0956	Lstg_0952	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.595
rph	spoT	Lstg_0956	Lstg_0951	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.554
rph	tdcF	Lstg_0956	Lstg_0950	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	L-PSP (mRNA) endoribonuclease.	0.684
rph	yicC	Lstg_0956	Lstg_0954	Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	Putative stress-induced protein.	0.541
rpoZ	Lstg_0948	Lstg_0952	Lstg_0948	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	Hypothetical protein.	0.627