Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hapEFlavin containing monooxygenase. (511 aa)    
Predicted Functional Partners:
aes_2
Lipase.
 
 
  0.651
fadH
2,4-dienoyl-CoA reductase.
     
 0.592
Lstg_1863
acyl-CoA synthetase.
  
 0.550
aes_1
Alpha/beta hydrolase.
 
 
  0.490
alkJ_2
Alcohol dehydrogenase (acceptor).
  
    0.482
Lstg_2379
Cytochrome P450.
 
 0.481
Lstg_0064
Ankyrin repeats (3 copies).
  
 
   0.480
alkJ_1
Alcohol dehydrogenase (acceptor).
  
    0.475
aspB
Aspartate aminotransferase.
    
  0.472
Lstg_2124
Sterol desaturase-related protein.
  
     0.469
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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