Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aspBAspartate aminotransferase. (390 aa)    
Predicted Functional Partners:
pheA_1
Chorismate mutase/prephenate dehydratase.
  
 
  0.862
lysAC_1
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC).
 
 
 0.858
pheA_2
2-methylcitrate synthase.
    
  0.852
lysAC_2
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.837
aroF
Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
    
  0.830
Lstg_1863
acyl-CoA synthetase.
  
 0.740
pdhB_2
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
    
 0.638
putA
Bifunctional PutA protein (proline dehydrogenase/ delta-1-pyrroline-5-carboxylate dehydrogenase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.615
lgrB
Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.586
trpE
Anthranilate synthase.
   
 0.575
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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