STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plaOuter membrane protease. (308 aa)    
Predicted Functional Partners:
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.781
minE
Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.730
Lstg_0785
SET domain protein.
  
     0.719
Lstg_1228
Calcium-transporting ATPase.
  
     0.718
Lstg_3319
Hypothetical protein.
  
     0.712
celC
Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.705
Lstg_2730
Von Willebrand factor type A domain protein.
  
     0.704
Lstg_1381
2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase.
  
     0.699
Lstg_3230
L-gulono-gamma-lactone oxidase.
  
     0.691
Lstg_0160
Photosystem I assembly protein Ycf3.
  
     0.683
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.