STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbpE_1Beta-lactamase. (512 aa)    
Predicted Functional Partners:
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.694
ptpA_2
Prolyl oligopeptidase.
 
     0.672
pbpE_3
Serine-type D-Ala-D-Ala carboxypeptidase.
  
     0.656
Lstg_0054
Hypothetical protein.
  
     0.582
Lstg_1318
Hypothetical protein.
 
     0.572
Lstg_2884
HD domain protein.
  
     0.545
cpg2_1
Carboxypeptidase G2.
  
     0.541
ftsI
Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.535
mrcA
Putative peptidoglycan synthetase, penicillin-binding protein 1A.
     
 0.530
rodA
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
    
  0.490
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
Server load: medium (48%) [HD]