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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ubiA4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (280 aa)    
Predicted Functional Partners:
ubiC
4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
    
 0.979
ubiD_2
3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family.
 
  
 0.976
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
  
  
  0.972
ubiD_1
3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family.
 
  
 0.940
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.916
ispB
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.913
visC
Oxidoreductase with FAD/NAD(P)-binding domain protein.
  
  
  0.860
Lstg_1971
Tfp type 4 fimbrial pilin related signal peptide protein domain protein.
       0.770
etfD
Electron transfer flavoprotein-ubiquinon; Accepts electrons from ETF and reduces ubiquinone.
 
 
 0.698
ubiG
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 0.656
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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