STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lssXLegionella secretion system protein X; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (200 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.995
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.938
Lstg_1994
Hypothetical protein; Belongs to the UPF0250 family.
  
  
 0.878
Lstg_1863
acyl-CoA synthetase.
   
 0.846
lssY
Legionella secretion system protein Y.
       0.802
pksL_1
Polyketide synthase.
   
 0.771
ppsE
Polyketide synthase, type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
   
 0.771
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
       0.758
lgrB
Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.753
Lstg_1386
acyl-CoA synthetase.
   
 0.749
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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