Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lstg_2104Hypothetical protein; Alpha-2-macroglobulin family N-terminal region. (1911 aa)    
Predicted Functional Partners:
pbpC
Penicillin binding protein 1C.
   
 0.982
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.677
Lstg_1174
IcmF.
  
    0.482
Lstg_2785
Type III restriction enzyme, res subunit.
  
   0.475
Lstg_1861
Hypothetical protein.
  
    0.470
ankK
Cardiac ankyrin repeat -containing protein K.
  
  
  0.455
luxR_1
LuxR family transcriptional regulator.
  
     0.417
Lstg_0911
Coiled-coil protein.
  
     0.408
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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