| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Hgd | Lstg_2070 | Lstg_0850 | Lstg_2070 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 0.506 |
| Hgd | argD | Lstg_0850 | Lstg_3433 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.707 |
| Hgd | bioA | Lstg_0850 | Lstg_2017 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.581 |
| Hgd | fadB | Lstg_0850 | Lstg_0236 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.775 |
| Hgd | garR | Lstg_0850 | Lstg_2133 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 3-hydroxyisobutyrate dehydrogenase. | 0.598 |
| Hgd | menB | Lstg_0850 | Lstg_0092 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | enoyl-CoA hydratase. | 0.768 |
| Hgd | ppsC | Lstg_0850 | Lstg_0906 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Quinone oxidoreductase. | 0.504 |
| Hgd | pta | Lstg_0850 | Lstg_0614 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Phosphate acetyl/butaryl transferase. | 0.880 |
| Hgd | yfcX | Lstg_0850 | Lstg_0351 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.775 |
| Lstg_2070 | Hgd | Lstg_2070 | Lstg_0850 | NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.506 |
| Lstg_2070 | garR | Lstg_2070 | Lstg_2133 | NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 3-hydroxyisobutyrate dehydrogenase. | 0.526 |
| Lstg_2070 | pta | Lstg_2070 | Lstg_0614 | NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Phosphate acetyl/butaryl transferase. | 0.834 |
| Lstg_2070 | yvgN | Lstg_2070 | Lstg_2132 | NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Oxidoreductase,aldo/keto reductase family. | 0.783 |
| argD | Hgd | Lstg_3433 | Lstg_0850 | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.707 |
| argD | bioA | Lstg_3433 | Lstg_2017 | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.643 |
| argD | garR | Lstg_3433 | Lstg_2133 | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 3-hydroxyisobutyrate dehydrogenase. | 0.567 |
| bioA | Hgd | Lstg_2017 | Lstg_0850 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.581 |
| bioA | argD | Lstg_2017 | Lstg_3433 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.643 |
| bioA | fadB | Lstg_2017 | Lstg_0236 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.472 |
| bioA | garR | Lstg_2017 | Lstg_2133 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 3-hydroxyisobutyrate dehydrogenase. | 0.547 |