| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| era | ftsY | Lstg_2450 | Lstg_1114 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.538 |
| era | gidB | Lstg_2450 | Lstg_2153 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.552 |
| era | trmE | Lstg_2450 | Lstg_0691 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.895 |
| ftsY | era | Lstg_1114 | Lstg_2450 | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.538 |
| ftsY | gidB | Lstg_1114 | Lstg_2153 | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.533 |
| ftsY | trmE | Lstg_1114 | Lstg_0691 | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.442 |
| ftsY | yidC | Lstg_1114 | Lstg_0690 | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.766 |
| gidA | gidB | Lstg_2154 | Lstg_2153 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.989 |
| gidA | parA_1 | Lstg_2154 | Lstg_2152 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Chromosome partitioning protein ParA. | 0.532 |
| gidA | parB_2 | Lstg_2154 | Lstg_2151 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Chromosome partitioning protein parB; Belongs to the ParB family. | 0.539 |
| gidA | trmE | Lstg_2154 | Lstg_0691 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.998 |
| gidA | yidC | Lstg_2154 | Lstg_0690 | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Cytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.669 |
| gidB | era | Lstg_2153 | Lstg_2450 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.552 |
| gidB | ftsY | Lstg_2153 | Lstg_1114 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.533 |
| gidB | gidA | Lstg_2153 | Lstg_2154 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.989 |
| gidB | parA_1 | Lstg_2153 | Lstg_2152 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Chromosome partitioning protein ParA. | 0.650 |
| gidB | parB_2 | Lstg_2153 | Lstg_2151 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Chromosome partitioning protein parB; Belongs to the ParB family. | 0.749 |
| gidB | parC | Lstg_2153 | Lstg_0716 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.535 |
| gidB | rpe | Lstg_2153 | Lstg_2790 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.551 |
| gidB | rsmE | Lstg_2153 | Lstg_2502 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.546 |
STRING v12.5 is now available!
