STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsPPhosphoenolpyruvate-protein phosphotransferase PtsP; Belongs to the PEP-utilizing enzyme family. (765 aa)    
Predicted Functional Partners:
ptsH
Sugar transport PTS system phosphocarrier HPr protein.
  
 
 0.992
cyaB_2
Guanylate/adenylate cyclase.
   
 0.804
cyaB_1
Guanylate cyclase.
   
  0.756
nudH
Nucleotide hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
 
  0.717
cyaA
Fused adenylate cyclase/two component hybrid sensor/regulator.
   
  0.707
cyaA_1
Adenylate/guanylate cyclase transmembrane protein.
    
  0.706
evgS
Sensory box histidine kinase/response regulator.
   
 0.704
cph2_2
Regulatory protein (GGDEF, PAS, PAC domains).
    
  0.703
gmr_1
Regulatory protein (GGDEF domain).
    
  0.692
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.637
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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