ppaX protein (Legionella steigerwaltii) - STRING interaction network

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[Homology]

Score

ppaX

HAD-superfamily hydrolase. (215 aa)

Predicted Functional Partners:

Lstg_2767

0.941

ribD

0.600

Lstg_2070

0.600

dprE1

0.588

guaA

0.583

Lstg_0542

0.564

hisF

0.563

rpe

0.532

hisH

0.528

Lstg_2550

0.518

Your Current Organism:

Legionella steigerwaltii

NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lstg_0542	Lstg_2767	Lstg_0542	Lstg_2767	Hypothetical protein.	Phosphatase.	0.504
Lstg_0542	ppaX	Lstg_0542	Lstg_2256	Hypothetical protein.	HAD-superfamily hydrolase.	0.564
Lstg_0542	ribD	Lstg_0542	Lstg_0059	Hypothetical protein.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.704
Lstg_2070	Lstg_2767	Lstg_2070	Lstg_2767	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Phosphatase.	0.601
Lstg_2070	dprE1	Lstg_2070	Lstg_0138	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Hypothetical protein.	0.651
Lstg_2070	ppaX	Lstg_2070	Lstg_2256	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	HAD-superfamily hydrolase.	0.600
Lstg_2550	Lstg_2767	Lstg_2550	Lstg_2767	Putative phosphotransferase.	Phosphatase.	0.551
Lstg_2550	ppaX	Lstg_2550	Lstg_2256	Putative phosphotransferase.	HAD-superfamily hydrolase.	0.518
Lstg_2767	Lstg_0542	Lstg_2767	Lstg_0542	Phosphatase.	Hypothetical protein.	0.504
Lstg_2767	Lstg_2070	Lstg_2767	Lstg_2070	Phosphatase.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.601
Lstg_2767	Lstg_2550	Lstg_2767	Lstg_2550	Phosphatase.	Putative phosphotransferase.	0.551
Lstg_2767	dprE1	Lstg_2767	Lstg_0138	Phosphatase.	Hypothetical protein.	0.588
Lstg_2767	guaA	Lstg_2767	Lstg_0295	Phosphatase.	GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.583
Lstg_2767	hisF	Lstg_2767	Lstg_0883	Phosphatase.	Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.563
Lstg_2767	hisH	Lstg_2767	Lstg_0881	Phosphatase.	Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.528
Lstg_2767	ppaX	Lstg_2767	Lstg_2256	Phosphatase.	HAD-superfamily hydrolase.	0.941
Lstg_2767	ribD	Lstg_2767	Lstg_0059	Phosphatase.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.600
dprE1	Lstg_2070	Lstg_0138	Lstg_2070	Hypothetical protein.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.651
dprE1	Lstg_2767	Lstg_0138	Lstg_2767	Hypothetical protein.	Phosphatase.	0.588
dprE1	ppaX	Lstg_0138	Lstg_2256	Hypothetical protein.	HAD-superfamily hydrolase.	0.588