STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
drgANitroreductase. (201 aa)    
Predicted Functional Partners:
Lstg_1863
acyl-CoA synthetase.
 
 0.911
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.767
Lstg_2962
Putative conserved hypothetical proteins.
 
  
 0.760
moeZ_3
Thiazole biosynthesis adenylyltransferase ThiF.
    
 0.754
Lstg_2395
Hypothetical protein.
  
    0.738
moeZ_4
Putative molybdenum cofactor synthesis protein 3.
    
 0.728
hmp
Oxidoreductase, FAD-binding protein.
  
 
 0.704
Lstg_1855
Pterin-4-alpha-carbinolamine dehydratase.
   
 
  0.696
fadH
2,4-dienoyl-CoA reductase.
  
 
 0.673
nemA
NADH-dependent flavin oxidoreductase, Oye family.
  
 
 0.656
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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