Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
copA_1Copper transporting P-type ATPase. (738 aa)    
Predicted Functional Partners:
copA_2
Copper efflux ATPase.
 
 
 0.798
ctpA_2
Cation efflux transporter.
   
  0.632
cueO
Multicopper oxidase.
 
 
  0.578
copA_2-2
Multicopper oxidase.
  
 
  0.577
copA2
Copper efflux ATPase.
  
 
  0.562
gmr_4
Diguanylate kinase.
       0.539
Lstg_3046
Hypothetical protein.
       0.532
prs_3
Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family.
       0.466
pdp_2
Thymidine phosphorylase.
       0.464
Lstg_3049
Metallo-beta lactamase family transporter protein.
       0.458
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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