STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
prs_3Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (301 aa)    
Predicted Functional Partners:
pdp_2
Thymidine phosphorylase.
 
  
  0.960
pdhB_2
Pyruvate/2-oxoglutarate dehydrogenase subunit E1.
   
 0.848
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
  
 
0.844
pdp_1
Thymidine phosphorylase.
 
  
  0.831
Lstg_3049
Metallo-beta lactamase family transporter protein.
 
     0.812
ctpA_2
Cation efflux transporter.
  
    0.789
cusA_3
Chemiosmotic efflux system B protein A.
       0.773
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.740
lysS
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.724
odpB
Pyruvate dehydrogenase E1 subunit beta.
   
 0.721
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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