Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lstg_3116Putative Antitoxin higA-2. (104 aa)    
Predicted Functional Partners:
higB_2
Toxin higB-2.
 
 
 
 0.990
mrgA_1
Ferritin; Belongs to the Dps family.
   
    0.511
mrgA_2
DNA-binding protein; Belongs to the Dps family.
   
    0.511
Lstg_3118
Hypothetical protein.
       0.503
Lstg_3119
AAA-like domain protein.
       0.503
Lstg_2998
Hypothetical protein.
  
   
 0.474
sohA_2
Putative regulator PrlF.
     
 0.468
Lstg_1465
Serine protein kinase.
   
    0.454
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.436
higB_1
mRNA interferase HigB.
  
   
 0.423
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.