hit protein (Legionella steigerwaltii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

hit

Histidine triad (HIT) protein. (140 aa)

Predicted Functional Partners:

Lstg_2785

0.792

Lstg_3350

0.772

rpoC

0.724

rpoZ

0.695

Lstg_2379

0.529

Lstg_0666

0.489

nudH

0.489

ywlE

0.480

btuE

0.476

rhlE

0.402

Your Current Organism:

Legionella steigerwaltii

NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lstg_0666	hit	Lstg_0666	Lstg_3349	MutT/nudix family transporter protein.	Histidine triad (HIT) protein.	0.489
Lstg_0666	rhlE	Lstg_0666	Lstg_1875	MutT/nudix family transporter protein.	ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family.	0.875
Lstg_2379	btuE	Lstg_2379	Lstg_3348	Cytochrome P450.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.675
Lstg_2379	hit	Lstg_2379	Lstg_3349	Cytochrome P450.	Histidine triad (HIT) protein.	0.529
Lstg_2785	hit	Lstg_2785	Lstg_3349	Type III restriction enzyme, res subunit.	Histidine triad (HIT) protein.	0.792
Lstg_2785	rpoC	Lstg_2785	Lstg_2577	Type III restriction enzyme, res subunit.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.915
Lstg_2785	rpoZ	Lstg_2785	Lstg_0952	Type III restriction enzyme, res subunit.	RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.996
Lstg_3350	btuE	Lstg_3350	Lstg_3348	MATE efflux family protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.418
Lstg_3350	hit	Lstg_3350	Lstg_3349	MATE efflux family protein.	Histidine triad (HIT) protein.	0.772
btuE	Lstg_2379	Lstg_3348	Lstg_2379	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Cytochrome P450.	0.675
btuE	Lstg_3350	Lstg_3348	Lstg_3350	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	MATE efflux family protein.	0.418
btuE	hit	Lstg_3348	Lstg_3349	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Histidine triad (HIT) protein.	0.476
hit	Lstg_0666	Lstg_3349	Lstg_0666	Histidine triad (HIT) protein.	MutT/nudix family transporter protein.	0.489
hit	Lstg_2379	Lstg_3349	Lstg_2379	Histidine triad (HIT) protein.	Cytochrome P450.	0.529
hit	Lstg_2785	Lstg_3349	Lstg_2785	Histidine triad (HIT) protein.	Type III restriction enzyme, res subunit.	0.792
hit	Lstg_3350	Lstg_3349	Lstg_3350	Histidine triad (HIT) protein.	MATE efflux family protein.	0.772
hit	btuE	Lstg_3349	Lstg_3348	Histidine triad (HIT) protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.476
hit	nudH	Lstg_3349	Lstg_2176	Histidine triad (HIT) protein.	Nucleotide hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.	0.489
hit	rhlE	Lstg_3349	Lstg_1875	Histidine triad (HIT) protein.	ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family.	0.402
hit	rpoC	Lstg_3349	Lstg_2577	Histidine triad (HIT) protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.724