Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fixJ_1Sigma 54-dependent response regulator. (150 aa)    
Predicted Functional Partners:
qseC_2
Two component sensor kinase.
 
 0.980
arcB_1
Sensory box histidine kinase/response regulator.
 
 
 0.854
luxQ_1
Sensory histidine-kinase / response regulator.
 
 
 0.840
bvgS
Sensory box histidine kinase/response regulator.
 
 
 0.835
evgS
Sensory box histidine kinase/response regulator.
 
 
 0.805
Lstg_2866
Sensory histidine kinase AtoS.
 
 0.801
cph1
Two-component sensor histidine kinase.
 
 
  0.791
gmr_1
Regulatory protein (GGDEF domain).
   
 0.774
cpxR_1
Transcriptional regulatory protein CpxR.
  
  
  0.724
cpxR_2
Transcriptional regulatory protein CpxR.
  
  
  0.713
Your Current Organism:
Legionella steigerwaltii
NCBI taxonomy Id: 460
Other names: ATCC 35302, CCUG 29674, CCUG 56441, CIP 103851, DSM 23076, JCM 7558, L. steigerwaltii, NCTC 11991, strain SC-18-C9
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