Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0011TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: met:M446_0007 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. (112 aa)    
Predicted Functional Partners:
Mnod_0009
PFAM: BolA family protein; KEGG: met:M446_0006 BolA family protein; Belongs to the BolA/IbaG family.
 
 
 0.991
Mnod_6742
PFAM: BolA family protein; KEGG: met:M446_6494 BolA family protein; Belongs to the BolA/IbaG family.
 
 
 0.946
Mnod_5953
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.865
Mnod_0010
PFAM: protein of unknown function DUF29; KEGG: mrd:Mrad2831_1125 hypothetical protein.
  
    0.838
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
       0.771
Mnod_2171
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: met:M446_2468 iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 0.680
Mnod_3325
TIGRFAM: FeS assembly scaffold SufA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: met:M446_4331 FeS assembly scaffold SufA; Belongs to the HesB/IscA family.
 
 0.667
Mnod_4666
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
 
 
 0.647
Mnod_4021
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: met:M446_3583 iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 0.640
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 
   0.631
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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